Use a mattress cleaning service or make your own cleaning materials You lose dead skin cells every night while sleeping, which sift through your sheets and end up on your mattress. Dust mites that feed on those skin cells feel the same way. Mold and mildew can form on some mattresses, especially if you sweat a lot while sleeping or live in a humid environment. If you have allergies or asthma, a dirty mattress aggravates your symptoms. Old mattresses, of…